In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
May 22 2024Massachusetts General Hospital In new research, investigators at Massachusetts General Hospital show that the 100-year-old Bacillus Calmette-Guérin vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
Denise Faustman, MD, PhD, senior author, director of the Immunobiology Laboratory at MGH and Associate Professor of Medicine at Harvard Medical School The MGH Phase II and Phase III clinical trials testing BCG differed from other BCG trials in important ways. Instead of receiving one dose of BCG, participants received five or six doses of a particularly potent strain of BCG vaccine. The US participants were followed for a total of 36 months instead of weeks or months. "We know that in people who are naïve to BCG vaccine, the off-target effects can take at least two years to achieve full protection," said Faustman.
Related StoriesDuring the earlier Phase II trial when the virus was more lethal but less transmissible, the BCG vaccine's efficacy was 92%, comparable to the efficacy of the Pfizer and Moderna COVID-19 vaccines in healthy adults.
Vaccine BCG Vaccine Cell Covid-19 Diabetes Efficacy Hospital Laboratory Medical School Medicine Omicron Pandemic Placebo Research SARS SARS-Cov-2 Tuberculosis Type 1 Diabetes Virus
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Century-old vaccine found to protect type 1 diabetics from infectious diseasesIn new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
Read more »
The £12 a night seaside holiday park with a heated pool, crazy golf and moreFamilies say it's a 'fantastic park' which they'd '100% recommend'
Read more »
Businessman Sir Anthony O'Reilly dies after short illnessHe built an international media business which at one stage owned more than 100 newspapers.
Read more »
Crime boss busted as police raid finds guns, drugs, and cashDavid Smith, 35, had sawn-off shotguns and drug 100 times stronger than heroin
Read more »
McDonald's launches new Mix 'N' Match meal deal for £3 from todayThere are more than 100 different combinations up for grabs
Read more »
Glasgow city set for 100 Orange walks and loyalist parades in matter of weeksGlasgow is braced for 100 Orange walks and loyalist parades across the months of June and July as notifications are sent for scores of marches to take place across the city.
Read more »