A Billion-Year Evolutionary Tale – Biologists Trace Cell Division Back to Its Roots

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A Billion-Year Evolutionary Tale – Biologists Trace Cell Division Back to Its Roots
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Ichthyosporeans Sphaeroforma arctica and Chromosphaera perkinsii undergoing mitosis, depicted as two halves of a cell, rendered in Haeckel-inspired tones and a naturalist style. Credit: Nirupa Rao

Despite last sharing a common ancestor over a billion years ago, animals and fungi are similar in many ways. Both belong to a broader group called ‘eukaryotes’ – organisms whose cells store their genetic material inside a closed compartment called the ‘nucleus’. The two differ, however, in how they carry out many physiological processes, including the most common type of cell division – mitosis.

Hiral Shah, an EIPOD fellow working across the three groups, led the study. “Having recognized very early that Ichthyosporea, with their many nuclei and key evolutionary position between animal and fungi, were well-suited for addressing this question, it was clear that this would require bringing together the cell biological and technical expertise of the Dey, Dudin, and Schwab groups, and this is exactly what the EIPOD fellowship allowed me to do,” said Shah.

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