Houston-based rBIO has invented a new process to churn out insulin at higher yields using custom-made bacteria.
Recent measures by Congress cap monthly out-of-pocket costs at $35 for Medicare recipients, and insulin-makers have cut their list prices for certain products, but not all patients stand to benefit. One biotech startup, rBIO of Houston, is aiming to make insulin more affordable by producing a copycat version of the drug—known as a biosimilar. It’s not the only company developing biosimilar insulin, but it says it has invented a new process to do so using custom-made bacteria.
coli-like bacteria that can produce much greater amounts of insulin than existing strains used in insulin production. To do that, the company struck up a collaboration with Sergej Djuranovic, a professor of cell biology and physiology at Washington University School of Medicine in St. Louis. In 2019, Djuranovic's lab discovered a sequence of amino acids—the building blocks of proteins—that could make a gene produce far more proteins than is usual.
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