Study reveals significant impairments in the quality of life for adults with hen's egg white allergy, highlighting the need for accurate food labeling and further research into effective treatments.
By Tarun Sai LomteReviewed by Susha Cheriyedath, M.Sc.Nov 27 2024 New study sheds light on the daily struggles and fears faced by adults living with hen's egg white allergy, calling for urgent improvements in food labeling and treatment options.
EWA is the second most prevalent food allergy in children, and it mostly resolves by school age. However, it is rare in adults and is described in case reports only. Research has identified two allergens in egg yolk and four in egg white . Ovomucoid is considered the most clinically relevant component as it shows heat and gastric acid stability.
In the present study, researchers assessed HRQoL in adults with EWA. They screened an electronic database for patients aged ≥ 18 with increased levels of specific immunoglobulin E against egg yolk, egg white, ovomucoid, or ovalbumin from October 2015 to February 2022. Data on age, sex, and clinically relevant sensitization were collected. Clinically relevant sensitization was defined as any anaphylactic or allergic reaction after egg white consumption.
The FAIM included six items related to product avoidance, impact on social life, and perceived chance of accidental exposure. Questions were scored on a seven-point scale, with higher scores indicating greater HRQoL impairment. In addition, participants were asked to specify the age at which the allergy first manifested and the most severe symptom following exposure to the egg allergen.
Six individuals reported dyspnea, a grade IIIA symptom. One participant reported severe anaphylaxis with skin and respiratory reaction and hypotension, requiring a visit to the emergency department. The overall mean FAQoLQ score was 4.64. However, based on age at onset, the mean score was 4.49 for adulthood onset and 4.99 for childhood onset.
Allergen Anaphylaxis Children Diet Dyspnea Food Food Allergy Heat Immunotherapy Pain Research Respiratory Skin Stomach Stomach Pain
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