Gastroschisis, a congenital abdominal wall defect, has transformed from a uniformly fatal condition to one with a 95% survival rate through surgical advancements over the past six decades.
Xia & He Publishing Inc.Nov 8 2024 The primary goal of managing gastroschisis is to mitigate fetal and postnatal risks, including damage from herniated bowel loops and ensuring effective decompression of the gastrointestinal tract during recovery. This review focuses on both preventative and corrective aspects of gastroschisis management, highlighting innovations in neonatal surgery that improve quality of life and long-term health outcomes.
Embryo-pathogenesis Although environmental factors primarily influence gastroschisis, the exact pathogenesis remains unclear. Proposed theories suggest a combination of abdominal wall defects and increased intraabdominal pressure leads to herniation. This review provides insights into intrauterine events and hindgut anomalies that can affect development, offering evidence from experimental models and prenatal monitoring to advance understanding of the condition's origins.
Antenatal and perinatal management Early diagnosis via ultrasound enables detailed prenatal monitoring and the option for delivery at specialized centers. The optimal timing for delivery is around 37–38 weeks, ideally via vaginal delivery to avoid complications linked to cesarean sections. Upon birth, careful handling of exposed bowel and temperature regulation are critical to prevent further injury.
Appendix Bladder Colon Gastroenterology Gastrointestinal Tract Healthcare Malrotation Nutrition Omphalocele Prenatal Research Surgery Volvulus
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