The ovary is an essential organ for female fertility, and its age-dependent decline in function is a major cause of infertility. However, the molecular mechanisms underlying ovarian aging are still not well understood, particularly in higher vertebrates like primates.
Aging hallmarks of the primate ovary revealed by spatiotemporal transcriptomics," wasSomatic cells in the non-follicle region of the ovary undergo more significant transcriptional changes with age compared to those in the follicle region, suggesting that this area may be more susceptible to aging and could contribute to a hostile microenvironment that accelerates ovarian aging.
With advancing age, a subpopulation of MT2high cells accumulates, potentially spreading and amplifying senescent signals throughout the ovary.underlying ovarian aging. These findings could lead to the identification of biomarkers and therapeutic targets for aging and age-related ovarian disorders, ultimately contributing to improved fertility treatments and interventions for women.
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.Apr 17, 2024Use this form if you have come across a typo, inaccuracy or would like to send an edit request for the content on this page. For general inquiries, please use ourThank you for taking time to provide your feedback to the editors.
Your feedback is important to us. However, we do not guarantee individual replies due to the high volume of messages.to let the recipient know who sent the email. Neither your address nor the recipient's address will be used for any other purpose. The information you enter will appear in your e-mail message and is not retained by Medical Xpress in any form.Get weekly and/or daily updates delivered to your inbox.
Medicine Research Health Research News Health Research Health Science Medicine Science
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Geraniol alleviates cognitive decline in D-galactose-induced aging miceA new research paper was published in Aging (listed by MEDLINE/PubMed as 'Aging (Albany NY)' and 'Aging-US' by Web of Science) Volume 16, Issue 6, entitled, 'Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model.
Read more »
Evidence of a pan-tissue decline in stemness during human agingA new research paper was published on the cover of Aging, entitled, 'Evidence of a pan-tissue decline in stemness during human aging.'
Read more »
Sarah Paulson, 49, talks aging gracefully without Botox: 'I don't shoot anything into my face'Sarah Paulson discussed aging with actor Pedro Pascal and revealed that she does not currently use Botox or other cosmetic practices to keep her looking young at age 49.
Read more »
Sarah Paulson, 49, talks aging gracefully without Botox: 'I don't shoot anything into my face'Sarah Paulson discussed aging with actor Pedro Pascal and revealed that she does not currently use Botox or other cosmetic practices to keep her looking young at age 49.
Read more »
Sarah Paulson, 49, talks aging gracefully without Botox: 'I don't shoot anything into my face'Sarah Paulson puts on a stylish display as she arrives to the Louis Vuitton runway show during Paris Fashion Week. The stunning 49-year old actress dons a white and blue pinstripe gown with a pink skirt.
Read more »
Calorie restriction study reveals complexities in how diet impacts agingPenn State researchers may have uncovered another layer of complexity in the mystery of how diet impacts aging.
Read more »