AI-powered ECG model predicts heart disease risk with precision

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AI-powered ECG model predicts heart disease risk with precision
HeartHeart DiseaseArrhythmia
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A new AI-enhanced ECG model, AIRE, accurately predicts mortality and heart disease risk, providing clinicians with actionable, patient-specific insights.

By Hugo Francisco de SouzaReviewed by Susha Cheriyedath, M.Sc.Nov 5 2024 Developed using data from diverse patient groups, AIRE’s advanced AI predicts heart disease risk and mortality with precision, giving clinicians tools for more targeted, long-term patient care.

Study findings revealed that the novel model can accurately predict all-cause mortality, ventricular arrhythmia, atherosclerotic CVD, and heart failure risk. Recent advances in computer processing capabilities and the advent of next-generation predictive machine learning models have sparked excitement in the research community.

“Existing mortality prediction models are limited by predicting survival at one or a small number of set timepoints and do not provide information on specific actionable pathways. A high-risk prediction is unhelpful to a clinician if there is no accompanying information on how to improve the survival trajectory of their patient.

AIRE’s unique approach uses patient-specific survival curves, allowing it to predict "time-to-mortality" rather than just providing set time-point risks. Additionally, five other models focusing on CV death , non-CV death , atherosclerotic cardiovascular disease , ventricular arrhythmia , and heart failure were derived using similar approaches.

Notably, AIRE was capable of accurately predicting heart failure events in participants without a personal or family history of CVD, which is especially relevant as conventional diagnoses in these populations are typically delayed.

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