Researchers provide a better understanding of the origin of eosinophils and eosinophilia, and the effects of treatments targeting them.
New fundamental research provides a better understanding of the origin of eosinophils and eosinophilia, and the effects of treatments targeting them
Despite their potential beneficial actions, eosinophils generally have a bad reputation among doctors. In common diseases such as allergic asthma and rhinosinusitis, eosinophils are abnormally numerous in the blood and tissues, a condition known as eosinophilia. Eosinophilia is a clinical sign that aids in diagnosing these"eosinophil-associated" diseases and guides their treatment. It is known that eosinophilia is driven by increased production of eosinophils by the bone marrow.
This detailed characterization work provides the community with simple-to-use methods and freely accessible bioinformatics data that will greatly facilitate future studies of eosinophils. Using these resources, the same study showed that IL-5 does not act as previously believed by researchers and clinicians. Most thought that IL-5 promoted the maturation of cells destined to become eosinophils and that IL-5-targeting treatments blocked this maturation.
Research reveals that adults with PTSD have a 2% smaller cerebellum than people without the disorder. The finding expands understanding of the cerebellum's role in the brain beyond balance and ...
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