Sun Health Explainer: Dementia and Alzheimer’s disease
A "GAME-CHANGING" drug shown to slow the progression of Alzheimer's is set to be approved in the UK., developed by pharmaceutical company Eisai, is a targeted antibody treatment that binds to amyloid - a protein which builds up in the brains of people living with the disease.The decision from the UK's medicines regulator is due to be announced shortly, but it is understood to have approved the treatment.
Professor John Hardy, chairman of molecular biology of neurological disease at the UCL Institute of Neurology, described the drug as "game-changing".In the old days you were going to get five years before nursing home, now you might get seven years before nursing home careIn November 2022, when the results of trials were published, he said lecanemab was “the beginning of the end” for Alzheimer’s.
"It slows the disease by about 25 to 30 per cent so, you know, maybe if in the old days you were going to get five years before nursing home, now you might get seven years before nursing home care," Prof Hardy added.This week's potential ruling by the safety watchdog will mean it can be prescribed privately in Britain for the first time.
The National Institute of Health and Care Excellence will then advise on whether it should be rolled out by the NHS.What are the early symptoms of cognitive decline?This will be more pronounced in some people, as they experience memory and thinking problems that are mild but still noticeable. This is described as mild cognitive impairment . Unlike dementia sufferers, people with MCI can still get on with day-to-day life.of 65 have MCI, according to Alzheimer's Research UK.Disorientation - confusion about time, date or placetasks, e.g. managing money, or cooking a mealThese symptoms may affect someone with MCI all the
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