Botox is a common – and largely safe – cosmetic treatment. But it has emerged there can be some lasting effects from long-term use.
A safe and sure-fire way to smooth wrinkles and fine lines? Or a toxin that fixes your features into a permanent "frozen" expression? Either way, Botox is big business.. Originally derived from a potent neurotoxin produced by bacteria, it works by blocking signals from the nerves that control the facial muscles. The muscles relax, and fine lines and wrinkles disappear. The result? A more youthful visage – for three to four months, at least.
Eleven people were hospitalised, and six were treated with an antitoxin because of concerns of botulism – a condition where the toxin spreads beyond the local site and attacks the central nervous system causing muscle As Ach causes muscles to contract, Botulinum toxins cause muscular paralysis. There are seven distinct forms of botulinum toxin, types A-G.reviewed the safety of cosmetic Botox injections, and concluded that reports of serious side effects such as those seen by the CDC were rare. For example, between 2002-03 onlyfor therapeutic uses of Botox than for cosmetic cases .
It's even possible that the Botox toxin could escape its location in the nerve terminal close to the muscle and travel into the wider central nervous system. In 2015, scientists led by Frederic Meunier at the University of Queensland in Australia used cutting-edge microscopes to view single molecules of botulinum toxinalong rat neurons .
Yet there is some evidence that long-term Botox use could have a psychological impact on patients. In a 2023 study, Mitchell Brin, a neurologist at the University of California, Irvine, and colleaguesof 10 women before and after they received Botox injections. During the functional magnetic resonance imaging of their brains, the subjects were shown photos of angry and happy faces interspersed with neutral photos.
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