Boosting levels of a deficient protein has clear survival benefits for people with the genetic condition alpha-1 antitrypsin deficiency (AATD), according to new research led by RCSI University of Medicine and Health Sciences.
The findings underscore a call to make augmentation therapy accessible to patients with AATD in Ireland and more widely across Europe.
The results, published today in the American Journal of Respiratory and Critical Care Medicine, showed that boosting levels of alpha-1 antitrypsin in these patients improved survival rates. Related StoriesThe research showed that the people with AATD in Switzerland and Austria benefitted from a clear survival advantage due to augmentation therapy that people with AATD in Ireland do not.
"As this therapy is not currently reimbursed in Ireland or in several other European countries, this international collaboration generates further evidence of efficacy for the only specific treatment for the lung disease caused by this condition," she said.
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