Autoimmune diseases are complex illnesses, the causes of which are diverse and have not yet been fully explained. A research team at MedUni Vienna has now discovered an immunoregulatory protein that could be linked to the development of autoimmune diseases such as rheumatoid arthritis. The identified component of the immune system is called 'Rinl,' which could provide a new target for the development of immunomodulatory therapies. The study results were recently published in the Journal of Experimental Medicine.
Autoimmune diseases are complex illnesses, the causes of which are diverse and have not yet been fully explained. A research team at MedUni Vienna has now discovered an immunoregulatory protein that could be linked to the development of autoimmune diseases such as rheumatoid arthritis. The identified component of the immune system is called"Rinl," which could provide a new target for the development of immunomodulatory therapies.
While a deficiency or excess of Rin 1-3 proteins has already been linked in recent years in international studies, for example, to cancer, Alzheimer's disease or the spinal disease scoliosis, Rinl has so far been little researched.has been clarified by the scientific team as part of the current study.
Tfh are a subset of T cells and support the maturation of other essential components of the immune system, the B cells. Mature B cells, in turn, produce highly effective antibodies and thus play a major role in the body's immune response: in vaccinations, a large amount of such antibodies is desired, but in
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