AVAnT1A study: Investigating early COVID-19 vaccination and type 1 diabetes risk in high-risk children

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AVAnT1A study: Investigating early COVID-19 vaccination and type 1 diabetes risk in high-risk children
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Type 1 diabetes is an autoimmune disease that leads to disrupted glucose metabolism. It requires lifelong insulin therapy.

May 8 2024Helmholtz Munich ) The Global Platform for the Prevention of Autoimmune Diabetes collaborates within a European network to develop new methods to prevent this condition which is, to date incurable. AVAnT1A is GPPAD's third intervention study. It will investigate whether vaccination against SARS -CoV-2 in the first year of life can protect children who have an increased genetic risk for type 1 diabetes from developing the condition. The study is supported by funding from The Leona M.

COVID-19 has increased the risk of the disease. We have seen that children who had COVID-19 before age 18 months were around five times more likely to develop the islet autoantibodies as those who were not infected." New study aims to clarify correlation In a new study, GPPAD aims to further investigate this relationship. The AVAnT1A Study - short for "AntiViral Action against Type 1 Autoimmunity" - examines whether vaccination against COVID-19 at the age of six months can prevent the development of islet autoantibodies in babies at increased genetic risk of developing type 1 diabetes, thus reducing their risk of developing the condition.

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Diabetes SARS SARS-Cov-2 Type 1 Diabetes Adolescents Autoantibodies Autoimmune Disease Autoimmunity Blood Covid-19 Genetic Glucose Glucose Metabolism Hospital Immune System Insulin Metabolism Pancreas Pandemic Placebo Research Vaccine

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