A study in the CDC's Emerging Infectious Disease Journal reports the spread of H5N1 avian influenza among cats and dairy cattle in Texas and Kansas, showing systemic illness in cattle and significant fatalities in cats exposed to the virus through infected milk.
By Dr. Chinta SidharthanMay 1 2024Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the United States Centers for Disease Control and Prevention ’s Emerging Infectious Disease Journal, a team of scientists reported the spread of the highly pathogenic hemagglutinin 5 neuraminidase 1 avian influenza clade 2.3.4.4b among cats and dairy cattle in the states of Texas and Kansas.
The current avian influenza outbreak also poses more serious concerns since the clade has also been detected in severe cases of infections among humans in Chile and Ecuador. Recent reports from northern Texas, northeastern New Mexico, and southwestern Kansas reported a disease among dairy cattle that affected the quality and appearance of milk for a duration of approximately two weeks.
Histopathology analyses were performed on the cerebellum, cerebrum, eye, heart, kidney, liver, lung, lymph node, and spleen obtained during the postmortem analysis of the cats. Additionally, paraffin-embedded tissues from the cats and cattle were processed for immunohistochemistry analyses using antibodies against the primary influenza A virus.
Related StoriesMammary gland lesions in cattle in study of highly pathogenic avian influenza A clade 2.3.4.4b virus infection in domestic dairy cattle and cats, United States, 2024. A, B) Mammary gland tissue sections stained with hematoxylin and eosin. A) Arrowheads indicate segmental loss within open secretory mammary alveoli. Original magnification ×40. B) Arrowheads indicate epithelial degeneration and necrosis lining alveoli with intraluminal sloughing.
Avian Influenza H5N1 Heart Immunohistochemistry Influenza Laboratory Magnification Mammary Gland Necrosis Research RNA Spleen Virus
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