The victim, 23, was taken to hospital and pronounced dead a short time later.
West Yorkshire Police were called by the ambulance service to reports of an incident at an address in Winrose Avenue, Belle Isle, Leeds at 00:17 GMT on Tuesday.
Senior investigating officer Det Ch Insp James Entwistle said the man’s death was an “absolute tragedy”. “His death, in such a sudden and violent way, is an absolute tragedy and we will be continuing to support his family at what is clearly a very difficult time for them, while working to get them the answers they need."
Officers are also carrying out house-to-house inquiries in the area and asking people to check CCTV, doorbell and dashcam footage.
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