Beyond the lungs: SARS-CoV-2's multi-organ impact revealed

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Beyond the lungs: SARS-CoV-2's multi-organ impact revealed
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Beyond the lungs: SARS-CoV-2's multi-organ impact revealed Nature covid SARSCoV2 COVID19 memory memoryloss

By Pooja Toshniwal PahariaJul 5 2023Reviewed by Lily Ramsey, LLM In a recent review published in the Cell Death Discovery Journal, researchers elucidated the mechanisms underlying the impact of severe acute respiratory syndrome coronavirus 2 infections on the brain and recall.

Long COVID can result in persistent symptoms such as tiredness, frequent headaches, breathlessness, motor dysfunction, and concentration and memory difficulties.About the review In the present review, researchers present the mechanisms by which SARS-CoV-2 could infect the brain and affect memory. They also discussed long COVID risk factors and prevention strategies.

Persistent SARS-CoV-2 replication and SARS-CoV-2 spike protein-host ACE2 receptor interactions might lead to syncytia development and increase cytokine and autoantibody synthesis, thereby affecting brain function and memory in the long run. Dysregulated cytokine production can result in cytokine storms, leading to serious illnesses that increase COVID symptoms.

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