Bibliometric analysis reveals research trends connecting Alzheimer's disease and the gut microbiome Nutrients_MDPI Alzheimers Alzheimersdisease disease microbiome gut gutmicrobiome
By Dr. Priyom Bose, Ph.D.Jul 25 2023Reviewed by Benedette Cuffari, M.Sc. Alzheimer’s disease is a neurodegenerative disorder that is primarily diagnosed in the elderly. Although AD is prevalent throughout the world, the exact cause and underlying mechanisms responsible for this disease remain unclear.
Background The human gut microbiome is involved with many physiological processes, including those affecting the central nervous system , immune system, and endocrine system. Although the gut microbiome is a possible contributor to AD pathophysiology, the exact etiology remains unclear. About the study The current study utilized bibliometric analysis to map research trends and identify hotspots linked to AD and the gut microbiome. Herein, the researchers aimed to provide important insights into the dynamic trends, intellectual structure, and prospective hotspots in this domain, which will help guide future research in the right direction.
A total of 67 countries throughout the world, including the United States, China, Germany, Italy, Canada, Japan, Spain, Australia, and the United Kingdom, have contributed to this field of research. This indicates a global interest in research related to AD and the gut microbiome. Although the top three contributors of, China, the U.S., and Italy have similar amounts of publications on gut microbiota and AD, the U.S. leads in terms of citation count. This indicates that research in this field conducted by the U.S. is particularly ground-breaking.
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