Blood Pressure Control and Changes in Cerebral Small Vessel Disease Biomarkers

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Blood Pressure Control and Changes in Cerebral Small Vessel Disease Biomarkers
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Keeping a tighter rein on blood pressure in adults over 50 is desirable for brain health jamanetworkopen

CBF indicates cerebral blood flow; DTI, diffusion tensor imaging; FA, fractional anisotropy; FLAIR, fluid-attenuated inversion recovery; MD, mean diffusivity; SBP, systolic blood pressure; and WMLs, white matter lesions.

Figure 2. Patterns of Changes in the Type III White Matter Parcellation Map–Derived Deep White Matter Regions of Interest When Comparing Intensive Treatment With Standard TreatmentA, Changes in white matter lesions. B, Changes in diffusion tensor imaging fractional anisotropy. C, Changes in DTI mean diffusivity. The red-yellow color scale indicates effect size; that is, smaller increase over time for intensive treatment compared with standard treatment.

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