Blood test predicts preeclampsia risk in laboring women

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Blood test predicts preeclampsia risk in laboring women
Blood TestAlbuminAnesthesiology
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A simple blood test could help doctors identify women in labor who are at risk for preeclampsia -; a leading cause of maternal death -; and take precautions to prevent it, according to research presented at the ANESTHESIOLOGY 2024 annual meeting.

American Society of AnesthesiologistsOct 20 2024 A simple blood test could help doctors identify women in labor who are at risk for preeclampsia -; a leading cause of maternal death -; and take precautions to prevent it, according to research presented at the ANESTHESIOLOGY® 2024 annual meeting.

Researchers have determined doctors can predict a woman's risk of developing preeclampsia by calculating the ratio of two blood proteins -; fibrinogen and albumin -; measured in routine blood tests done when women in labor enter the hospital. Fibrinogen is involved in blood clotting and inflammation, while albumin helps maintain fluid balance and carries hormones, vitamins and enzymes throughout the body.

In the study, researchers analyzed the records of 2,629 women who gave birth between 2018 and 2024, 1,819 who did not have preeclampsia, 584 who had preeclampsia with mild features or symptoms , and 226 who had preeclampsia with severe features or symptoms . The researchers determined those who had a higher FAR were more likely to develop preeclampsia than those with a lower FAR.

While FAR has been associated with other inflammatory conditions, its specific application to preeclampsia and preeclampsia with severe symptoms has not been reported in a group this large and racially diverse. Our study shows that FAR can be a predictive tool that gives anesthesiologists and obstetricians a new method for assessing a laboring mom's risk of developing preeclampsia when they are admitted to the hospital.

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