Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer - Nature Biomedical Engineering

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Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer - Nature Biomedical Engineering
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Mineralization of bone matrix regulates tumor cell growth cornell natBME

We thank all members of the Fischbach lab for valuable discussions of this research; the Wiesner group for providing fluorescent silica nanoparticles; J. Kuo for help with illustrations; L. O’Keeffe for help with preparation of bone scaffolds; the Cornell Animal Health Diagnostic Core for paraffin embedding and sectioning; J. Massague for providing bone tropic BoM1-2287 and BoM-1833; and the Cornell Center for Animal Resources and Education staff for animal care.

Caryl and Israel Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USARobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY, USADepartment of Materials Science and Engineering, Cornell University, Ithaca, NY, USAKavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, NY,...

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