A biobank for all, in which a person from any background could find a bone marrow donor for a stem cell transplant, is a major goal for stem cell science. While repositories of cell lines that could be a match for most patients are successfully materializing in some countries with genetically homogenous populations like Japan and the United Kingdom, how many more we need for a universal solution remains unknown.
, but only 12% of relatives end up being a match. A global biobank could reduce these pressures, but it is unknown how many samples would provide an adequate diversity of cell lines.
To find the ideal number of donor cell lines in Brazil, the research team used data from the Brazilian National Registry of Bone Marrow Donors . From over 4 million individuals, the researchers identified nearly 2,000 cell lines that could act as potential universal donors. The team then calculated how many of these cell lines would be a match for most of the Brazilian population, and they estimated 51, 157, 267, and 559 cell lines would provide 50%, 75%, 85%, and 95% coverage, respectively. They also predicted over 4 million individuals would need to be tested to cover 99% of Brazilians.
Notably, only 30 cell lines were enough to be a donor match for almost 40% of Brazilians. Using the Allele Frequency Net Database (AFND, which compiles
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Carabao Cup fourth round draw - Newcastle United get Manchester UnitedNewcastle United get Manchester United - Carabao Cup fourth round draw
Read more »
Leeds United, Sheffield United and more fans to benefit from LNER newsFootball fans can struggle to get home after late Sunday kick offs but extra LNER trains may help amid broadcast schedule changes.
Read more »
Antony back in England and set to meet policeManchester United winger Antony has returned to England from Brazil and is set to meet police over assault allegations, which he denies. Antony is under investigation by Greater Manchester Police (GMP) after his former partner Gabriela Cavallin alleged he assaulted her on separate occasions between June 2022 and May this year. The United player is currently on a leave of absence but returned to England on Tuesday. Antony has also spoken to Sao Paulo police over Cavallin&8217;s allegations but has been permitted to leave Brazil. Cavallin had alleged in an interview with Brazil news outlet UOL,...
Read more »
Brazil's banana spider aids erectile dysfunction treatmentThree decades ago, Brazilian researchers began studying a curious side effect from banana spider bites: the toxin left victims with priapism, a painful and persistent erection.
Read more »
Antony returns to UK from Brazil and agrees to meet police over allegationsThe 23-year-old Manchester United winger denied all allegations in a statement on social media earlier this month.
Read more »