Breast milk antibodies linked to protection against rotavirus in infants

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Breast milk antibodies linked to protection against rotavirus in infants
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A study led by researchers at the University of Rochester Medical Center found that breast milk provides protection against rotavirus, a common gastrointestinal disease that causes diarrhea, vomiting and fever in infants.

University of Rochester Medical CenterOct 1 2024 Babies whose mothers had high levels of specific antibodies in their breast milk were able to fend off the infection for a longer period than infants whose mothers had lower levels. The findings are expected to drive future research to improve infant health through optimized breastfeeding practices.

The research, led by Dr. Kirsi Jarvinen-Seppo, MD, PhD, professor in the Division of Allergy and Immunology at UR Medicine Golisano Children's Hospital , tracked antibody levels and kinetics over time to analyze antibody responses to a wide range of respiratory, diarrheal and sepsis pathogens in human milk. The study's primary aim was to understand the protective properties of these antibodies and how they vary across different geographic and economic regions.

Dr. Kirsi Jarvinen-Seppo, MD, PhD, Professor in the Division of Allergy and Immunology at UR Medicine Golisano Children's Hospital Related Stories"The variation in antibody profiles between regions highlights the impact of economic and environmental factors on maternal immunity," said Jarvinen-Seppo.

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Breast Milk Antibody Breastfeeding Children Diarrhea Fever Gastrointestinal Disease Research Respiratory Rotavirus Vomiting

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