Researchers looked for links between providing care for mental health issues and reductions in chemotherapy-related toxicities.
symptoms are linked to an increased risk for severe chemotherapy toxicity in older adults with cancer. This risk is mitigated by geriatric assessment -driven interventions.Researchers conducted a secondary analysis of a randomized controlled trial evaluating GA-driven interventions vs standard care to reduce grade 3 chemotherapy-related toxicities in older adults with cancer.
Mental health was assessed using the Mental Health Inventory 13, and chemotherapy toxicity was graded by the National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0. The study was conducted at City of Hope National Medical Center in Duarte, California, and patients were followed throughout treatment or for up to 6 months from starting chemotherapy.According to the authors, patients with depression had increased chemotherapy toxicity in the standard-of-care arm and for demographic, disease, and treatment factors .
The authors state that depression was associated with increased odds of hematologic-only toxicities in the standard-of-care arm.
Toxicology Toxicity Poisoning Toxins Chemotherapy Lung Cancer Lung Carcinoma Cancer Of The Lung Colorectal Cancer Colorectal Cancer (CRC) Breast Cancer Malignant Breast Neoplasm Breast Carcinoma Prostate Carcinoma Malignant Prostate Neoplasm Prostate Cancer Cancer Of The Prostate Geriatrics Elder Care Geriatric Medicine Older Adults Seniors Senior Citizens Elderly
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