Depression is associated with a significantly increased risk for cardiovascular disease (CVD), particularly in women, new data show.
is linked to a significantly increased risk for cardiovascular disease , particularly in women, new data from a large retrospective cohort study show. Researchers suggest that screening and treating patients for depression may lead to a decreased incidence of CVD.Researchers analyzed health insurance claims from more than 4 million Japanese patients filed between 2005 and 2022.
Investigators followed participants for a mean period of 2.5-3.5 years to observe the number of CVD events in those who had a diagnosis of depression. During the follow-up period, there were 119,000 CVD events in men and 61,800 CVD events in women .Compared with women without depression, those with depression had a 64% higher risk for CVD , while men with depression had a 39% higher risk for CVD vs their counterparts without depression (HR, 1.39;This association was significant even after controlling for various factors such as body mass index, diabetes, smoking, alcohol consumption, and physical inactivity.
Investigators offered several theories about the increased risk for CVD in women with depression, including how depression during hormonal shifts can contribute to a greater impact on cardiovascular health."Healthcare professionals must recognize the important role of depression in the development of CVD and emphasize the importance of a comprehensive, patient-centered approach to its prevention and management," study author Hidehiro Kaneko, MD, said in a.
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