Cardamom (Elettaria cardamomum (L.) Maton) Seeds Intake Increases Energy Expenditure and Reduces Fat Mass in Mice by Modulating Neural Circuits That Regulate Adipose Tissue Lipolysis and Mitochondrial Oxidative Metabolism in Liver and Skeletal Muscle

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Cardamom (Elettaria cardamomum (L.) Maton) Seeds Intake Increases Energy Expenditure and Reduces Fat Mass in Mice by Modulating Neural Circuits That Regulate Adipose Tissue Lipolysis and Mitochondrial Oxidative Metabolism in Liver and Skeletal Muscle
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Study shows cardamom increases appetite, burns fat tamu

). This amount of bioactive compounds for mice of ~30-g average body weight corresponds to 15.8, 31.7 and 63.4 mg bioactives/kg per day, which multiplied by the animal Km factor and divided by the human Km factor will give a human dose equivalent of 1.28, 2.57 and 5.14 mg bioactives/kg per day, respectively. The Km factor is obtained by dividing body weight and BSA and used for drug dose conversion between mg/kg and mg/m].

GC-FID analyses were carried out on trace GC Ultra gas chromatograph equipped with an auto sampler with a RX-5MS capillary column which was coupled to a mass spectrometer . The column temperature was programmed to rise from 50 to 280 °C at a rate of 3 °C/min. The carrier gas was helium with a flow rate of 1.5 mL/min. Scan time and mass range were 1 s and 50–550, respectively, and the acquired data were processed using Xcalibur software .

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