CDC reports on vaccine effectiveness of bivalent COVID-19 vaccine among vaccinated vs. unvaccinated adults aged ≥65 years in 2022-23 CDCMMWR vaccine effectiveness vaccineeffectiveness covid COVID19 SARSCoV2 unvaccinated vaccinated bivalent
By Neha MathurJun 19 2023Reviewed by Lily Ramsey, LLM In a recent Morbidity and Mortality Weekly Report , the United States Centers for Disease Control and Prevention reported how coronavirus disease 2019 mortality rates varied among unvaccinated and vaccinated adults aged ≥65 years in the United States between 2022 and 2023.
Following these vaccine programs, studies analyzed COVID-19 cases and mortality rates by vaccination status soon after authorization of bivalent COVID-19 vaccines, which showed these vaccines conferred additional protection. The CDC retrieved study data, i.e., weekly counts of COVID-19–related deaths among unvaccinated individuals and bivalent booster recipients for September 18, 2022–April 1, 2023, from 20 U.S. jurisdictions. Note that the COVID-19 case surveillance data in the U.S. is linked to immunization registries and registration databases on a routine basis.
Observations Among those≥65 years who received a bivalent COVID-19 vaccine booster or remained unvaccinated, there were 8,161 COVID-19–related deaths across 20 U.S. jurisdictions between September 18, 2022, and April 1, 2023. The CDC also reported time-stratified mortality rates among unvaccinated and vaccinated people two weeks to two months after receiving a bivalent booster vaccination.
Conclusions To summarize, a bivalent COVID-19 booster vaccination provided substantial and durable protection against COVID-19–related death in adults aged ≥65 years.
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