Discover the critical challenges and groundbreaking advancements shaping biopharmaceutical formulation development.
Sponsored Content by Yokogawa Fluence AnalyticsReviewed by Olivia FrostDec 13 2024 Researchers involved in biopharmaceutical studies face various demands when developing therapeutic proteins, peptides, and RNA.This article explores the critical challenges and advancements in biopharmaceutical formulation development.
Drug delivery systems Effective and stable delivery systems are essential, especially for RNA-based therapies due to degradation. Tools capable of modeling bioprocessing stresses related to temperature or shear stress offer crucial insights into improving solution conditions necessary to maintain stability.
Immunogenicity Protein, peptide, and RNA therapeutic instability may cause immunogenicity. Advanced investigative equipment that offers insights into propensities for aggregation or degradation can alleviate these instabilities. Each sample cell has dedicated optics. This allows independent control of experimental parameters like temperature and stirring rate and enables a comprehensive stability assessment for different biologic classes.Integrating technologies like ARGEN into biopharmaceutical formulation development addresses specific technical demands, going beyond what can be achieved when developing innovative treatments.
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