Science, Space and Technology News 2024
A new universal flu vaccine candidate has shown promising results in animal models, providing protection against various influenza strains and paving the way for upcoming human trials.
The researchers hope to launch human clinical trials within 1-3 years, said virologist Naoko Uno, Ph.D., who led the new study. “We want to make sure our vaccine can span multiple seasons, not just one, and protect against all the strains that affect humans,” she said., but 2 of them—Influenza A and Influenza B—pose the greatest risks to humans. Seasonal flu vaccines include proteins from 3 or 4 circulating subtypes of those viruses, which include H1N1, H3N2 and IBV.
For the new work, the Cleveland Clinic researchers administered the vaccine candidate intranasally. Blood tests showed that 4 weeks later the animals had developed antibodies against the virus, and when the animals were exposed to the pathogen they were protected against developing infection.
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