Two classes of pervasive environmental chemicals that are present in household cleaners, furniture and electronics had 'surprising' effects specifically on the non-nerve cells in the brain.
Two classes of chemicals present in common household products may impair the development of oligodendrocytes, the myelinating cells of the central nervous system , which are critical to brain development and function. However, the researchers as well as outside experts agree more research is needed before any firm conclusions can be drawn.
They found that quaternary compounds were potently and selectively cytotoxic to developing oligodendrocytes and that organophosphate flame retardants prematurely arrested oligodendrocyte maturation. These effects were confirmed in mice and cultured human oligodendrocytes. Children with urinary BDCIPP concentration within the third quartile also had significantly increased odds of motor dysfunction .
In his view, the results "provide a starting point to understand what exposure levels to these chemicals might be putting ourselves or kids at risk for toxicity.", Shaheen Lakhan, MD, a neurologist and researcher based in Miami, Florida, who was not involved in the study, echoed the need for more research.
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