A study published in BMCMedicine finds that eczema and psoriasis in adults are associated with increased incidence of anxiety and depression. Part of this risk can be mediated through modifiable risk factors, including sleeping problems.
This study is based in part on data from the CPRD, obtained under licence from the UK Medicines and Healthcare Products Regulatory Agency. The data are provided by patients and collected by the National Health Service as part of their care and support. The interpretation and conclusions contained in this study are those of the authors alone.
We are enormously grateful to all members of our Patient and Public Advisory Panel who have attended regular meetings and made invaluable contributions to the analysis and interpretation of this study based on their lived experience. This panel is represented by two authors who have reviewed and edited the manuscript.This study is funded by the NIHR Research for Patient Benefit Programme, PB-PG-0418-20025.
Alasdair D. Henderson, Elizabeth Adesanya, Amy Mulick, Julian Matthewman, Kathryn E. Mansfield & Sinéad M. Langan Patient and Public Advisory Panel, Skin Disease Epidemiology Research Group, London School of Hygiene & Tropical Medicine, London, UKCatherine H. SmithCamden & Islington NHS Foundation Trust, London, UK
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The secular trend of enterovirus A71 after the implementation of preventive measures in Taiwan - BMC Public HealthBackground Enterovirus A71 (EV A71) is one of the most important enteroviruses related to morbidity and mortality in children worldwide. This study aimed to analyse the secular trend of EV A71 in Taiwan from 1998 to 2020 and to evaluate the effectiveness of infection control measures. Methods We collected the epidemiological data of EV A71 from disease surveillance systems in Taiwan. We analysed the association between the secular trend of EV A71 and preventive measures such as hand washing, case isolation, and suspension of classes. Results The incidence of enterovirus infections with severe complications (EVSC) decreased from 16.25 per 100,000 children under six in 1998 to less than 9.73 per 100,000 children under six after 2012 (P = 0.0022). The mortality rate also decreased significantly, from 3.52 per 100,000 children under six in 1998 to 0 per 100,000 children under six in 2020 (P | 0.0001). The numbers of EVSC and fatalities were significantly higher in the years when EV A71 accounted for more than 10% of the annual predominant serotypes (p | 0.05). After the implementation of many non-pharmaceutical interventions in 2012, the incidence of EVSC and mortality rate decreased significantly (p | 0.001). Conclusions After implementing active enterovirus surveillance and preventive measures, we found that the incidence of EVSC and fatalities due to EV A71 in Taiwan decreased significantly from 1998 to 2020. Continuous surveillance and strengthened infection control policies are still needed in the future.
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