A major study found pregabalin raises heart failure risk, especially in older patients with heart disease.
A widely prescribed drug for nerve pain, anxiety and epilepsy has been linked to a significantly higher risk of heart failure, prompting calls for doctors to be more cautious when offering it to certain patients. Pregabalin, available on prescription in the UK, was associated with a 48 percent increased risk of developing heart failure, according to a major new study.
“Doctors should consider the cardiovascular risks of pregabalin, particularly for older or vulnerable patients,” the researchers said in their conclusion. Pregabalin works by altering the way nerves send messages to the brain and is often used when traditional painkillers fail to relieve nerve pain. While generally considered safe under medical supervision, the drug can cause side effects including headaches, diarrhoea, nausea, blurred vision and memory problems.
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