Complex Nanoparticles Could Boost Osteogenesis In Implants: SciReports nanoparticles bonetissueengineering tissueengineering
By Bhavna KavetiJul 26 2022Reviewed by Susha Cheriyedath, M.Sc. Graphene has found widespread applications in the field of bone tissue engineering due to its favorable physical and biological properties. Additionally, the unique properties of graphene, including high surface area and surface functionalization flexibility, make it a potential candidate for applications in bone tissue engineering.
The obtained nanosheets were characterized using ultraviolet-visible , Fourier transforms infrared spectroscopy, X-Ray diffraction , and Raman spectroscopy techniques, and the results demonstrated that BSA could successfully reduce GO facilitating the decoration of Sr nanoparticles on the reduced GO .
Nanomaterials for Bone Tissue Engineering The bone tissue engineering field came into the limelight nearly three decades ago. There has been tremendous progress in bone tissue engineering with exponentially increasing research. Bone tissue engineering focuses on alternative treatment options to eliminate issues of clinically used treatments such as donor site morbidity, limited availability, immune rejection, and pathogen transfer.
The large surface area of graphene nanosheets facilitates the synthesis of Sr nanoparticles on the graphene surface by simultaneous reduction of GO and Sr nanoparticles. Moreover, previous studies demonstrated that Sr nanoparticles based on BSA -rGO nanosheets could be used in bone tissue engineering due to enhanced graphene strength.
The UV-vis spectrum showed the characteristic peaks of GO at 225 and 310 nanometers that attributed to π-π and n-π interactions, respectively. Moreover, in rGO, the peak at 232 nanometers shifted to 260 nanometers, and the intensity of the peak at 310 nanometers decreased significantly. Conclusion To summarize, a facile approach toward BSA-mediated synthesis of Sr nanoparticle-decorated rGO nanosheets was demonstrated for their application in bone tissue engineering. Raman, UV–Vis, XRD, and FTIR spectroscopy results confirmed the role of BSA in reducing and decorating the Sr nanoparticles on the rGO nanosheet’s surface.
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