Dr. Andre Koernig discusses the evolving capabilities of atomic force microscopy (AFM), highlighting its applications in biological research.
From Bruker BioAFMReviewed by Emily MageeNov 13 2024 insights from industryDr. André KörnigApplication ScientistBruker BioAFM In this interview, Dr. André Körnig, Application Scientist at Bruker BioAFM discusses the applications of BioAFM in the life sciences. He highlights its versatility and ability to image biological samples without extensive preparation.
What makes AFM technology so special, and why is it important to continue developing it? I like AFM because it's quite intuitive; you can imagine it as the finger of a blindfolded person touching surfaces to feel their stiffness and topography. AFM is relatively straightforward to explain and use compared to other complex techniques, especially in biological applications.
Can you tell us about the multi-parametric imaging of fibroblasts and what it involves? Fibroblasts cells are quite robust and easy to work with, and a great model system for general imaging. Multi-parametric imaging means seeing the topography of the cells and measuring other properties like stiffness, adhesion, or even internal structures. We poke into the sample to measure how it reacts, which allows us to obtain mechanical properties like Young's modulus.
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