In the first trial of its kind, participants will be injected with a experimental vaccine and around month later exposed to Sars-Cov-2, the virus that causes the disease
But with levels of the virus spreading in the population still relatively low, the trials are the fastest way of testing the level of protection from a vaccine.
Dr Claire Waddington, clinical lecturer in infectious diseases at the University of Cambridge, said challenge trials are"well established as a way to accelerate the development of vaccines".
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