COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly ImmuneResponse Coronavirus Disease COVID Booster mRNA frontiersin
Study: Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals. Image Credit: The Imagineers / Shutterstock
In the current study, scientists have evaluated the long-term efficacy of the third booster dose of mRNA-based COVID-19 vaccine in older adults. Antibody response induced by mRNA COVID-19 vaccine The antibody level analyzed two months after the primary vaccination revealed a significant induction in response against wild-type SARS-CoV-2. However, a considerable proportion of participants showed low antibody response.
Related StoriesA significant induction in antibody response was observed against wild-type virus and tested variants at one-month post-booster vaccination. Even low responders showed a similar induction. However, a significant reduction in antibody response was observed at four months compared to one month.
Induction and waning of memory B and T cell response against Spike following booster vaccination. RBD-specific memory B , Spike-protein-specific CD8 , CD4 Th1 or CD4 Th2 responses. The frequency of IgG RBD-specific memory B cells among total IgG antibody-secreting cells is presented for memory B cell response. For CD8, CD4 Th1, and CD4 Th2 responses, data presented are spot forming units per million PBMC from paired samples at four time points.
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
New drug shows promise for fighting both COVID-19 and cancerWhile vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.
Read more »
Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccinesResearchers compared the waning of vaccine-induced immunity from two and three doses of mRNA COVID-19 Pfizer-BioNTech vaccine BNT162b2 by conducting a repeated serological study to assess the prolonged humoral response.
Read more »
Do SSRIs lower the risk of long COVID?Researchers conducted a retrospective study to determine whether SSRIs with immunomodulatory and antiplatelet properties can decrease the risk of post-acute sequelae of COVID-19 (PASC).
Read more »
I'm A Celeb's Matt Hancock 'shamed' by banner blasting him for Covid deathsA banner message directed at Matt Hancock flew over the I'm A Celebrity...Get Me Out of Here! camp on Tuesday and called for the MP to be removed from the jungle
Read more »
China's zero-COVID rules spark violent protests in GuangzhouSince the beginning of the week more than 5,000 new COVID cases have been reported in the city of Guangzhou, both symptomatic and asymptomatic. Restrictions have sparked protests in the street
Read more »
Matt Hancock: Covid campaigners fly banner over I'm A Celebrity jungleCovid family groups fly a message for the former health secretary over the I'm A Celebrity camp.
Read more »