COVID vaccines averted infection in 10% of patient-facing healthcare staff during second wave

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COVID vaccines averted infection in 10% of patient-facing healthcare staff during second wave
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COVID vaccines averted infection in 10% of patient-facing healthcare staff during secondwave bmj_latest

today compared the effectiveness of the Pfizer-BioNTech and the Oxford-AstraZeneca COVID-19 vaccines against infection in 317,341 health and social care workers in England vaccinated between 4 January and 28 February 2021.

Using a combination of statistical and mathematical modeling, they analyzed data from 18,284 clinical, support, and administrative staff with no evidence of previous infection who were recruited from 105 NHS hospital trusts in England as part of the SARS-CoV-2 Immunity and Reinfection Evaluation Study.

Infections peaked in late December 2020 and decreased from January 2021, in line with rapid vaccination coverage among healthcare workers and a national lockdown.were being under 25 years old, living in a household of five or more people, having frequent exposure to patients with COVID-19, working in an emergency department or inpatient ward setting, and being a healthcare assistant.

This is an observational study, so can't establish cause, and limitations include the lack of detail needed to explore variations in hospital infection prevention and control policies, and differences in individuals' behavior that may have affected the results.

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