CRC Screening in Primary Care: The Blood Test Option

Colorectal Cancer News

CRC Screening in Primary Care: The Blood Test Option
Colorectal Cancer (CRC)Cancer DiagnosticsBlood
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Will patients who are offered this option forego colonoscopy and instead opt for a blood test?

Hi, everyone. I'm Dr Kenny Lin. I am a family physician and associate director of the Lancaster General Hospital Family Medicine Residency , and I blog at,"the best screening test is the test that gets done." But should that maxim apply to the new blood-based screening test, Guardant Health Shield? This proprietary test, which costs $895 and is not generally covered by insurance,of more than 10,000 adults aged 45-84 at average risk for CRC. The test had an 87.

A big concern, however, is that the availability of a blood test may cause patients who would have otherwise been screened with colonoscopy or stool tests to switch to the blood test. Afound that offering a blood test to patients who decline screening colonoscopy saves additional lives, but at the cost of more than $377,000 per life-year gained.

In practice, this will increase the complexity of the CRC screening conversations we have with patients. We will need to be clear that the blood test is not yet endorsed by the USPSTF or any major guideline group and is a second-line test that will miss most precancerous polyps. As with the stool tests, it is essential to emphasize that a positive result must be followed by diagnostic colonoscopy.

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