'Dear Stoner: I know that you cannot OD by smoking weed, but what about ingesting it?'
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For THC, there are varying figures, ranging from 1,260 milligrams of THC per kilogram of body weight down to 666 mg/kg. Even going with the lowest figure, a 175-pound man would have to consume more than 53 whole grams of pure THC all at once. And pure THC isn't something you are going to find in even the purest shatter oils and waxes produced.
Need more perspective? Caffeine has an LD50 of 192 mg/kg, and nicotine is around 60 mg/kg. Alcohol doesn't necessarily have an LD50 that translates well, but if just .4 percent of your roughly 160 ounces of blood contains booze, you're not likely to wake up. Even synthetic, marijuana-derived pharmaceuticals have higher LD50 ratings than natural marijuana.
Now, if you mean can you eat enough to get sick or have a bad time? Absolutely — it happens to the best of us. I have gotten sick — spinning head, a sinking feeling in my stomach — from a too-strong edible . Or maybe it's just an overdose of chocolate. ....In any case, do I suggest finding your limits that way? No. And unfortunately, I can't tell you how much you'd have to eat before you'd boot your lunch — nor do I suggest finding out the hard way.
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