The empty Ringway Centre could be turned into apartments, a cinema, nightclub and food and drink outlets.
Image source,Under the plans, the new towers would reach 44, 48 and 56 storeys with works split into three phases.
A total of 1,750 flats would be built with spaces for bicycles, lockers and scooters, the developer said."Following the loss of similarly important buildings such as Central Library, little remains of this chapter in the city's life, and with the loss of the Ringway, Birmingham will have almost obliterated memory of this time for future generations," a spokesperson said.
The 20th Century Society said the block was of high heritage significance and the site's overall heritage significance "has been undersold and the level of harm that would be caused through the building's total loss downplayed".Follow BBC West Midlands on