Women are twice as likely as men to suffer from depression and often experience more severe physical symptoms.
Xi'an Jiaotong-Liverpool UniversityNov 26 2024 This gender difference is particularly evident during reproductive years and dramatically impacts the lives of hundreds of millions of people worldwide. However, although links between mental health and reproductive health have been found, the associations have remained underexplored.
We used a specialised technique called Mendelian randomisation to analyse genetic variation and identify specific genes that may mediate the effect of depression on menstrual pain. "We found that increased sleep disturbances could exacerbate menstrual pain. Addressing sleep issues may therefore be crucial in managing both conditions. However, more research is required to understand the intricate links between these factors," says Liu.
Related StoriesLiu says: "Mental disorders are often not considered when treating conditions such as period pain. Our findings emphasize the importance of mental health screening for people who suffer from severe menstrual pain. We hope this can lead to more personalised treatment options, and improved healthcare, and reduce the stigma surrounding the conditions.
Pain Period Pain Bioinformatics Dysmenorrhea Genetic Menstrual Pain Mental Health Research Sleep
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