Data do not back the use of diacerin, resveratrol, or botulinum toxin for knee OA, according to the results of well-performed, multicenter, randomized controlled clinical trials.
VIENNA — Data do not back the use of diacerein or resveratrol for managing the pain of knee osteoarthritis , according to the results of two well-performed, multicenter, double-blind, randomized controlled clinical trials., PhD, an associate professor at the University of Tasmania in Hobart, Tasmania, Australia."There are only a few acceptable quality trials to date, and the results are inconsistent," Aitken added.
Individuals in the diacerein group were treated with an oral dose of 50 mg once daily for the first 2 weeks. If tolerated, the dose was increased to 50 mg twice daily. There was also no effect of resveratrol vs placebo on a host of secondary outcomes measured at 3 and 6 months. Results showed a nonsignificant trend favoring BoNT-A use, with the standard mean difference in pain of 0.35 , −0.27 , and −0.43 for short-, intermediate-, and long-term use, respectively.
Generalized Osteoarthritis OA - Osteoarthritis DJD - Degenerative Joint Disease Degenerative Arthritis Generalised Osteoarthritis Osteoarthritis (OA) Pain Management Botox Pain Management Botulinum Toxin In Pain Management Pain Management With Botox Injection Pain Management With Botulinum Toxin Pain Knee Pain Botox Botulinum Toxin Botox Injection Toxicology Toxicity
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