Study finds slightly higher risk in children at 10 years, but experts say this shouldn't change current supplementation recommendations.
However, at least for now, several apparently larger benefits for children from fish oil supplementation during pregnancy appear to outweigh this possible adverse effect, experts said.are the latest from a Danish prospective clinical trial of 736 pregnant women and their offspring. The women were randomized to 2.4 g n-3 long-chain polyunsaturated fatty acids or placebo daily from pregnancy week 24 until 1 week post-birth.
Prior to this recommendation, there was already guidance for women of childbearing age to consume 250 mg/d of EPA and DHA through diet and to increase DHA intake by 100-200 mg during pregnancy. This was primarily for nutritional reasons to support fetal brain development, Olsen said. The expert guidance regarding the use of fish oil supplementation to reduce the risk for preterm birth is based on several years of accumulated data, noted Olsen, who was one of the review's authors.In the new study, compared with 274 children in the control group, the 282 children of fish oil-supplemented pregnancies had a higher average BMI at age 10 years . There were no differences in weight, height, waist circumference, or the prevalence of obesity or underweight.
All 556 children had their body composition assessed by a bioelectrical impedance analysis scan. Those in the n-3 LCPUFA supplementation group had higher lean mass than those in the control group, after adjustment for age and sex. They also had higher metabolic syndrome scores . The Lundbeck Foundation, the Ministry of Health, the Danish Council for Strategic Research, and the Capital Region Research Foundation have provided core support to the COPSAC research center. Olsen had no disclosures.
Miriam E. Tucker is a freelance journalist based in the Washington, DC, area. She is a regular contributor to Medscape, with other work appearing in the Washington Post, NPR's Shots blog, and Diatribe. She is on X @MiriamETucker.All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC. This website also contains material copyrighted by 3rd parties.
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