Ever since one child, dubbed the 'Mississippi baby,' went into drug-free remission of HIV in 2013, experts have wondered if giving treatment within hours of birth might do the same for others.
The results of a new trial conducted in Africa suggest it can: Four out of six newborns infected at birth with“This is the first study to rigorously replicate and expand upon the outcomes observed in the Mississippi case report,” noted lead study author Dr. Deborah Persaud, who also reported the Mississippi case.According to Persaud, the new findings could change "the treatment paradigm for this infection that currently afflicts 1.7 million children around the world.
Four of the six did achieve hoped-for remission from HIV, defined as undetectable HIV after 48 weeks without treatment. However, "if we can get the virus to such low levels that we might be able to use some newer, innovative treatments to keep them from needing medication every day, then we're setting them up for success with long-term virologic control," she explained.
Speaking in a hospital news release, Chadwick said it's not clear how early treatment pushes HIV into remission in the very young but not older patients. “The idea that we're doing this in neonates is very novel," she said in the Lurie news release. "It's taking this idea of getting ART into the babies
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