Early extracorporeal life support (ECLS) does not improve survival in patients with acute myocardial infarction complicated by cardiogenic shock who are scheduled for early revascularization, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.
Cardiogenic shock is the leading cause of death in hospitalized patients with acute myocardial infarction. Evidence-based treatment is limited to immediate revascularisation of the culprit lesion. However, mortality remains high, reaching 40-50% within 30 days. Ongoing efforts to improve outcomes have led to an increase in the use of active mechanical circulatory support devices to achieve hemodynamic stabilization in severe shock.
ECLS-SHOCK was the first randomized trial to investigate the effect of ECLS on mortality in patients with acute myocardial infarction complicated by cardiogenic shock. A total of 420 patients with acute myocardial infarction and cardiogenic shock scheduled for early revascularisation were enrolled from 44 centers in Germany and Slovenia. The median age of participants was 63 years and 19% were women.
A total of 417 patients were included in the final analyses. The primary endpoint of all-cause death at 30 days occurred in 100 of 209 patients in the ECLS group and in 102 of 208 patients in the control group . Regarding safety endpoints, moderate or severe bleeding occurred more frequently in the ECLS group: 23.4% of patients in the ECLS group versus 9.6% of patients in the control group . Peripheral vascular complications requiring intervention occurred also more often in the ECLS group: 11.0% of patients in the ECLS group versus 3.8% of patients in the control group .
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Mortality data for early extracorporeal life support: ECLS-SHOCK trialEarly extracorporeal life support (ECLS) does not improve survival in patients with acute myocardial infarction complicated by cardiogenic shock who are scheduled for early revascularization, according to late breaking research presented in a Hot Line session at ESC Congress 2023.
Read more »
Creamfields set times and line up for final day on SundayThe final day of the festival will go out in style
Read more »
Three ways Man City could line up vs Sheffield Utd in the Premier LeagueManchester City travel to Bramall Lane to take on newly-promoted Sheffield United on Sunday, with Pep Guardiola absent after undergoing back surgery.
Read more »
Albon: Williams F1 straight-line reputation "not true" in ZandvoortWilliams Formula 1 driver Alex Albon says the team no longer has its traditional top speed advantage to exploit in Sunday's Dutch Grand Prix due to running more downforce.
Read more »
Neil Oliver leans into 'conspiracy' nickname with new line of T-shirtsTWO weeks into his boycott of Sainsbury’s for the crime of having security cameras at the tills, TV presenter-cum-conspiracy theorist Neil Oliver…
Read more »
Liverpool line-ups for Newcastle as Wataru Endo and Joe Goemz decisions madePaul Gorst and Ian Doyle name their preferred XIs for the upcoming clash with Newcastle in the Premier League
Read more »