Effects of time-restricted eating and calorie restriction on sex hormones

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Effects of time-restricted eating and calorie restriction on sex hormones
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The effects of time-restricted eating (TRE) and caloric restriction (CR) on sex hormones.

By Tarun Sai LomteJun 14 2024Reviewed by Lily Ramsey, LLM A recent study published in the European Journal of Clinical Nutrition evaluated the effects of time-restricted eating and caloric restriction on sex hormones.

Despite the health benefits of TRE, there have been concerns about its impact on sex hormones. That is, some research claims that TRE may negatively affect estrogen levels, which might lead to irregularities in the menstrual cycle and fertility issues. About the study In the present study, researchers evaluated the effects of TRE on reproductive hormones in males and pre- and post-menopausal females compared to CR, and no intervention was performed over 12 months.

TRE subjects ate ad libitum between 12 and 8 pm and fasted subsequently with energy-free beverages until noon the next day for the initial six months. During the maintenance phase, the TRE window was extended . A two-way analysis of covariance compared changes between groups. The relationship between sex hormones and body weight was evaluated using Spearman or Pearson correlation coefficients.

However, there were no differences between CR and TRE groups. SHBG, DHEA, and total testosterone levels in females and males were unchanged over time and between groups.

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