Evaluating CGM accuracy and benefits in non-diabetic populations

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Evaluating CGM accuracy and benefits in non-diabetic populations
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A new narrative review led by researchers at UCL and Birmingham Children's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD).

University College LondonJun 27 2024 A new narrative review led by researchers at UCL and Birmingham Children 's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors in people not living with diabetes .

For those living with diabetes, CGMs are less burdensome and offer real-time trends in glucose changes compared to older testing methods, such as regular finger prick blood tests. Some claim to tailor a person's diet and activity to help keep blood glucose within 'normal' levels. But what constitutes a normal blood sugar level varies between individuals and in the same individuals at different times, and CGM accuracy varies between CGM models." "With this in mind, we wanted to see what research had been undertaken into the use of CGMs in people who do not have diabetes.

Related StoriesThe review concludes that there is a lack of consistent and high-quality evidence to support CGM use in PNLD. For instance, there is little evidence to show how accurate CGMs are at measuring blood glucose levels or detecting changes in PNLD, nor sufficient research into the value and utility of the CGM data obtained in PNLD.

Dr Brown, who is based at the UCL Centre of Obesity Research, said: "While there are some benefits to personalised health programmes offered by commercial providers, including getting people to think about what and how much they're eating, the fact is that we don't have the same health outcome data for CGM use in people not living with diabetes.

Co-author John Pemberton, a Specialist Paediatric Diabetes Dietitian from Birmingham Children's Hospital who sits on the International Federation of Clinical Chemistry and Laboratory Medicine Working Group on CGM, said: "CGMs with an accuracy within 20% of actual blood glucose levels, at least 95% of the time, represent current market leading performance, and are extremely helpful for people with diabetes to make daily treatment decisions.

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