Evolving treatment paradigms in multiple myeloma could improve patient outcomes

Multiple Myeloma News

Evolving treatment paradigms in multiple myeloma could improve patient outcomes
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The treatment landscape for multiple myeloma, the second most common blood cancer, is shifting rapidly, with newly diagnosed patients increasingly being treated with a four-part drug combination that includes a new immunotherapy agent.

May 24 2024University of Miami Miller School of Medicine The , the second most common blood cancer , is shifting rapidly, with newly diagnosed patients increasingly being treated with a four-part drug combination that includes a new immunotherapy agent.

"These are great improvements for patients, and they deliver deep responses," said Landgren, chief of the Myeloma Division and director of the Myeloma Research Institute at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. The studies are testing the hypothesis that the addition of an antibody will provide deeper responses in more patients, and a longer duration of the clinical benefit of progression-free and overall survival. The implications are that patients can live longer without having the disease come back, and live longer overall.It could have additional implications beyond the clinical outcomes, and impact how we use other therapies.

Related StoriesTell us more about potentially reducing the need for bone marrow and stem cell transplantation. Key factors are access to newer drugs as well as treatment traditions. For instance, not all drugs are available in all countries outside the U.S., and within the U.S. some physicians are early adopters while others are slower to update treatment strategies. Myeloma experts who treat large numbers of patients may feel more comfortable implementing newer strategies sooner, compared to more general hematology/oncology physicians who only treat a handful of new multiple myeloma patients every year.

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