Falling folate levels sound alarm for urgent UK food fortification

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Falling folate levels sound alarm for urgent UK food fortification
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A study from the University of Cambridge used UK National Diet and Nutrition Survey data from 2008-2019 to examine folate levels, particularly in females of reproductive age. The study found a significant decline in both RBC and serum folate concentrations across all age groups, emphasizing the need for mandatory folic acid fortification in the UK.

By Vijay Kumar MalesuOct 16 2023Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in The American Journal of Clinical Nutrition, researchers at the University of Cambridge assessed pre-fortification United Kingdom folate trends , especially in females of reproductive age, using National Diet and Nutrition Survey data.

About the study The National Diet and Nutrition Survey Rolling Programme stands as a comprehensive governmental initiative in the UK, thoroughly gathering data on dietary intakes and nutritional status across various demographics. Annually, this survey reaches approximately 1,000 participants, comprising both adults and children from diverse regions within the UK. A significant subset of these participants also contribute blood samples for detailed biomarker analyses.

However, the survey faced challenges, particularly with the stability of samples, as an increasing number were received by the laboratory over 48 hours post-collection, raising concerns about the reliability of the data. Consequently, stringent criteria were applied, excluding delayed samples from Year 10 onwards.

Related StoriesIn an intriguing revelation, the geometric mean RBC folate and serum folate concentrations were typically higher in the youngest and oldest participants, with children aged 11 to 18 exhibiting the lowest concentrations. These concentrations were observed to decline over the study period. The exclusion of MeFox concentration from calculations led to a minor reduction in serum folate concentration across all demographics, yet the overall trends remained consistent.

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