A clinical trial of the drug benralizumab showed it was far more effective than conventional steroid tablets at treating life-threatening breathing difficulties in people with a severe form of the disease.
The first new treatment for asthma attacks in 50 years has been hailed as a 'game-changer' by doctors and patients. The monoclonal antibody specifically targets white blood cells that can invade the lungs of people with so-called eosinophilic asthma and cause the airways to swell and close up. The form of asthma accounts for around half of all emergency flare-ups of the disease.
But they don't always work so patients have to have repeated courses of the drugs, with a risk of re-admission to hospital and sometimes death. Regular use also increases the risk of diabetes and the bone-weakening disease osteoporosis. 'An amazing turnaround' Sheraz Hussein, 36, developed eosinophilic asthma 13 years ago. His condition spiralled out of control, with asthma attacks almost every day. But the benralizumab injection he had in hospital helped stabilise his disease.
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