Grey's Anatomy's 10 Most Memorable Villains, Ranked

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Grey's Anatomy's 10 Most Memorable Villains, Ranked
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Abigail double majored in English and French at UC Santa Barbara and completed an MPhil in Medieval Literature at Oxford University. She loves writing about pop culture and travel and produces a newsletter on these subjects in addition to writing for Screen Rant and undertaking other freelance projects.

Summary Throughout Grey's Anatomy, many villains, or at least antagonistic characters, help drive additional drama that keeps the show's core premises of romantic and professional entanglements alive. Most of these villains are just doing whatever serves their own career and Meredith just has the misfortune of being an obstacle to that.

His odd role in the story is why he is a memorable villain, as well as his fast turn to being a more friendly figure. Stark turns out to be very kind and supportive when Callie and her newborn daughter are hospitalized after a car crash. Stark isn't the most manipulative or noteworthy villain, but most people can at least recall him.

Boswell does not have that much interiority when she isn't on the show long enough to explore her worldview or why this is her personality. From the perspective of the audience, she is a plot device, who comes through the show to facilitate a tear-jerking break-up. However, Boswell still acts selfishly and leaves a disaster behind her on Grey's Anatomy, resulting in her being remembered as a villain.

6 Dr. Mark Sloan First Episode: Season 2, Episode 18, "Yesterday" Close Mark obviously became a character beloved by the Grey Sloan staff and the Grey's Anatomy fandom, even though many of his actions before becoming a father are inherently selfish. The first one — the one which frames him as a villain when he first appears in the show — is the worst.

Alex matures and becomes more compassionate later in the series, but some of his worst moments suggest that he never completely left behind being a villain. Namely, his tenure on Grey's Anatomy concludes when he breaks up with Jo in a letter after leaving her for Izzie. Alex may be one of the most memorable Grey's Anatomy villains because the audience actually liked him, making his faults that much worse.

There is a lot about the initial Mercy West conflict storyline that is wild and visceral before it ends in tragedy for some of these characters.

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